Cardiac Cycle Phases, Valvular Events, and Heart Sounds S1-S4
Phases of systole and diastole, isovolumetric periods, ejection/filling, and physiologic basis of S1-S4 heart sounds for clinical exams.
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Try it- 01The cardiac cycle lasts approximately 0.8 seconds at a heart rate of 75 beats per minute.This duration accounts for both systole and diastole.Flashify::Medical::Cardiovascular::Physiology
- 02Atrial systole contributes approximately 20-30 percent of total ventricular filling.The majority of filling occurs passively during early diastole.Flashify::Medical::Cardiovascular::Physiology
- 03The first heart sound (S1) is produced by the closure of the mitral and tricuspid (AV) valves.S1 marks the beginning of isovolumetric contraction.Flashify::Medical::Cardiovascular::Physiology
- 04During isovolumetric contraction, ventricular pressure rises rapidly while all four heart valves remain closed and volume remains constant.This phase occurs immediately after the QRS complex.Flashify::Medical::Cardiovascular::Physiology
- 05The second heart sound (S2) is produced by the closure of the aortic and pulmonic (semilunar) valves.S2 marks the end of ventricular systole and the start of diastole.Flashify::Medical::Cardiovascular::Physiology
- 06Physiologic splitting of S2 occurs during inspiration due to delayed closure of the pulmonic valve.Inspiration increases venous return to the right heart, prolonging RV ejection time.Flashify::Medical::Cardiovascular::Physiology
- 07The S3 heart sound occurs during early diastole due to rapid ventricular filling and is associated with volume-overload states.It is normal in children and young adults but often pathologic (e.g., HF) in older adults.Flashify::Medical::Cardiovascular::Physiology
- 08The S4 heart sound occurs in late diastole and is caused by atrial contraction into a stiff, non-compliant ventricle.S4 is always pathologic in adults over age 40.Flashify::Medical::Cardiovascular::Physiology
- 09Right-sided heart murmurs generally increase in intensity during inspiration.Inspiration decreases intrathoracic pressure, increasing venous return to the right side of the heart.Flashify::Medical::Cardiovascular::Physiology
- 10The dicrotic notch on an arterial pressure tracing corresponds to the closure of the aortic valve (S2).It represents a brief rise in pressure as the aortic valve snaps shut.Flashify::Medical::Cardiovascular::Physiology
- 11A normal left ventricular ejection fraction (LVEF) is approximately 55-70 percent.EF = (Stroke Volume / End-Diastolic Volume) x 100.Flashify::Medical::Cardiovascular::Physiology
- 12On an ECG, the P wave precedes atrial systole, while the QRS complex initiates ventricular systole.Electrical depolarization must precede mechanical contraction.Flashify::Medical::Cardiovascular::Physiology