Cardiac Cycle Phases, Valvular Events, and Heart Sounds S1-S4

Phases of systole and diastole, isovolumetric periods, ejection/filling, and physiologic basis of S1-S4 heart sounds for clinical exams.

12 cards· by GuruOwl

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  1. 01
    The cardiac cycle lasts approximately 0.8 seconds at a heart rate of 75 beats per minute.
    This duration accounts for both systole and diastole.
    Flashify::Medical::Cardiovascular::Physiology
  2. 02
    Atrial systole contributes approximately 20-30 percent of total ventricular filling.
    The majority of filling occurs passively during early diastole.
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  3. 03
    The first heart sound (S1) is produced by the closure of the mitral and tricuspid (AV) valves.
    S1 marks the beginning of isovolumetric contraction.
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  4. 04
    During isovolumetric contraction, ventricular pressure rises rapidly while all four heart valves remain closed and volume remains constant.
    This phase occurs immediately after the QRS complex.
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  5. 05
    The second heart sound (S2) is produced by the closure of the aortic and pulmonic (semilunar) valves.
    S2 marks the end of ventricular systole and the start of diastole.
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  6. 06
    Physiologic splitting of S2 occurs during inspiration due to delayed closure of the pulmonic valve.
    Inspiration increases venous return to the right heart, prolonging RV ejection time.
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  7. 07
    The S3 heart sound occurs during early diastole due to rapid ventricular filling and is associated with volume-overload states.
    It is normal in children and young adults but often pathologic (e.g., HF) in older adults.
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  8. 08
    The S4 heart sound occurs in late diastole and is caused by atrial contraction into a stiff, non-compliant ventricle.
    S4 is always pathologic in adults over age 40.
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  9. 09
    Right-sided heart murmurs generally increase in intensity during inspiration.
    Inspiration decreases intrathoracic pressure, increasing venous return to the right side of the heart.
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  10. 10
    The dicrotic notch on an arterial pressure tracing corresponds to the closure of the aortic valve (S2).
    It represents a brief rise in pressure as the aortic valve snaps shut.
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  11. 11
    A normal left ventricular ejection fraction (LVEF) is approximately 55-70 percent.
    EF = (Stroke Volume / End-Diastolic Volume) x 100.
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  12. 12
    On an ECG, the P wave precedes atrial systole, while the QRS complex initiates ventricular systole.
    Electrical depolarization must precede mechanical contraction.
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